Our Mission:
The LAM Foundation urgently seeks safe and effective treatments, and ultimately a cure, for lymphangioleiomyomatosis (LAM) through advocacy and the funding of promising research. We are dedicated to serving the scientific, medical and patient communities by offering information, resources and a worldwide network of hope and support. |
Current News
URMC Opens Clinic, Initiates Research on Rare Lung Disease in Women
May 14, 2013
Congratulations to our newest LAM Clinic, located in Rochester, NY, on this great article. Click here to view article. Be sure to listen to the very informative video included in the article.
LAM Cells Are Addicted to Glutamine
May 9, 2013
LAM Foundation-funded scientists Alfredo Csibi and John Blenis (Harvard Medical School) recently reported in the journal Cell that mTORC1, the protein that drives cell growth in LAM, directly stimulates the uptake and metabolism of glutamine, the most abundant amino acid in the body. The authors showed that mTORC1 regulates glutamine metabolism by repressing the mitochondrial protein SIRT4, which inhibits one of the steps required to produce energy from glutamine.
Importantly, their study suggests that therapies aimed at targeting nutrient metabolism could be efficacious in diseases with deregulated mTORC1 signaling including LAM.
Congratulations to Drs. Csibi and Blenis!
Click here to read the article in Cell (Cell 153, 1–15, May 9, 2013).
LAMposium Photos and Slideshow
Click here to view the LAMposium 2013 Slideshow created by Gina and Jurgen Lorenzen. This slideshow is created from all the pictures they took from the conference.
Click here to view and purchase photos from LAMposium 2013, the password is all4lam. All proceeds benefit the Foundation.
Currents
April 30, 2013
Click here to read April's issue of CURRENTS.
Emergency Room Quick Facts Card for LAM
The LAM Foundation is excited to offer LAM patients an easy way to provide doctors in the ER with information about LAM. We have designed a small card (the size of a typical business card) that is easy to carry and contains helpful information that you can share with the doctor when you go to an ER. The card can be inserted into a luggage tag and attached to a purse for easy reference.
Click here to print as many cards as you’d like using Avery 5881 business cards (perforated) or on card stock (hand-cut to size). You can also email the Foundation and request that a card be sent to you.
Currents
March 28, 2013
Click here to read March's issue of CURRENTS
The Sirolimus and Autophagy Inhibition in LAM (SAIL) research trial is currently seeking women with LAM
Brigham and Women’s Hospital, in Boston, MA is currently enrolling women with Lymphangioleiomyomatosis (LAM) in a clinical trial to test the safety of sirolimus (Rapamycin) in combination with hydroxychloroquine. All subjects will receive study drug provided by the trial.
Participation requires 7 visits over 1 year and involves physical exams, blood and urine samples, X-rays, CT scans, MRIs, breathing tests, exercise tests, questionnaires, and an at-home diary.
For more information including risks and study procedures please contact Betsy Peters, RN at 617-525-9331 or email at epeters2@partners.org.
TRAIL Trial Update:
The LAM Foundation is offering travel assistance for those participating in the TRAIL Trial and in need of financial assistance to make their participation possible.
For more information contact Tammy Roads,CCRC Project Manager
Phone 513-558-2148
Email: roadst@ucmail.uc.edu
LAM Clinics that are currently enrolling are:
The University of Cincinnati
Cleveland Clinic
Stanford University Medical Center
Washington University (St. Louis)
University of Miami
Swedish, Minor & James (Seattle)
Mayo Jacksonville
Sites opening soon
Loyola (Chicago)
Emory (Atlanta)
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