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Articles for tag Research

Science Friday: LAM Patients Help Power New Research


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Tags: Research ScienceFriday
Categories: Educational Resources

2018 Advances in LAM


With your support, The LAM Foundation continues to thrive as a source of hope for individuals affected by LAM. We have again accelerated research and improved patient care, with each day moving us closer to a cure. Learn more about a few of our 2018 accomplishments. 

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Tags: clinical care LAMposium 2018 patient support Research
Categories: News

Short-Term Goals, Long-Term Effects: Outcomes of the 2017 LAM Patient Benefit Conference


How can we improve the lives of LAM patients in five years or less? This is the question scientists, clinicians, and patients themselves gathered to answer at the first-ever LAM Patient Benefit Conference. Among the many valuable ideas shared, the following grant proposals have received funding to move forward. Each was chosen for its potential to result in solutions that will positively impact the diagnosis, care, or quality of life of LAM patients by the year 2023.

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Tags: Patient Benefit Conference Research
Categories: Events News

A Phase II Clinical Trial of an Aromatase Inhibitor for Postmenopausal Women with LAM


Lymphangioleiomyomatosis (LAM) predominantly affects women and can worsen with pregnancy, estrogen treatment, and the menstrual cycle, which suggested an important role for estrogen in the development and progression of this disease.

In preclinical laboratory studies, estrogen appeared to promote the growth and spread of LAM-like cells, while suppression of estrogen reduced the survival of LAM cells. In other human clinical trials, there has been a suggestion that lung function declines more slowly in LAM patients after menopause, although this was not clear when this clinical trial was being developed.

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Tags: Research
Categories: Educational Resources

Pulmonary Lymphangioleiomyomatosis (LAM): A Monogenic Neoplasm That Provides a Window into Cancer


The LAM community including LAM researchers, clinicians and patients has made incredible progress over the last 20 years. Frank McCormack and I were honored to write an invited review article “Lymphangioleiomyomatosis: A Monogenic Model of Malignancy” for the prestigious The Annual Review of Medicine, which covers significant developments in various fields of medicine since 1950.

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Tags: Research
Categories: Educational Resources

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