We Need Your Help to Fund LAM Research

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"The LAM community should be incredibly proud of the Foundation’s continuing role in fast-tracking the best LAM research” – Elizabeth Henske, MD

We need your help to fund LAM research. The LAM Foundation is the global leader in the fight against lymphangioleiomyomatosis (LAM). We are dedicated to finding safe and effective treatments, and ultimately a cure, for women living with LAM. By donating today, you can help give “A Breath of Hope” to women with LAM across the globe. 100% of your gift will go directly to LAM research.

The LAM Foundation has raised and invested nearly $25 million in research and patient support over the last 23 years. This has translated into a high-caliber network of passionate and engaged scientists that is priceless. Assuring scientific momentum to continue LAM research into the future is a key priority. LAM researcher and Clinic Director Elizabeth Henske, MD, notes “The impact of funding early-career LAM scientists cannot be over-emphasized. These young scientists bring energy, creativity, and passion, and often end up devoting their careers to LAM research.”

In 2012, Issam Ben-Sahra, PhD, a young scientist working at Harvard’s Manning lab, applied for and was awarded a Fellowship Grant from The LAM Foundation. This grant for $50,000 a year for three years supported Dr. Ben-Sahra’s early work. His research made an important discovery which may lead to new treatment targets for LAM. The findings, published twice in Science1,2 , describe two previously unknown functions of the mTOR pathway. These articles have since been cited over 400 times in scientific publications across the globe, promoting further research.

This initial investment from The LAM Foundation, provided by donors like you, has been leveraged into more than $1,260,000 in further grants from the Tuberous Sclerosis Alliance and the National Institutes of Health and National Cancer Institute (NIH/NCI), for an 8-fold investment impact. His mentor, Brendan Manning, PhD, noted “Clearly, the results of the research under Issam’s Fellowship Grant from The LAM Foundation led to these grants”. The NIH/NCI grant helped provide necessary funding for Dr. Ben-Sahra to set up his own lab at Northwestern University to continue his research in LAM.

This year, we are awarding Dr. Ben-Sahra a Career Development Grant for his work in Defining the mTORC1-dependent Signaling Mechanisms Mediating Epigenetic Modifications. Dr. Ben-Sahra says, “We hope that this project will eventually identify new therapeutic strategies to fight and eliminate LAM.” This grant is funded directly by your donations to The LAM Foundation.

This is just one story describing the impact that funding from The LAM Foundation can have. We believe in young scientists dedicated to LAM research, like Dr. Ben-Sahra. With your help, we will continue to nurture the careers of emerging scientists, new targets for therapy, and the potential for a cure for LAM.

This is just one story describing the impact that funding from The LAM Foundation can have. We believe in young scientists dedicated to LAM research, like Dr. Ben-Sahra. With your help, we will continue to nurture the careers of emerging scientists, new targets for therapy, and the potential for a cure for LAM.

CLICK HERE TO MAKE A DONATION TO THE LAM FOUNDATION.

With gratitude and hope,

Susan E. Sherman
Chief Executive Officer
The LAM Foundation

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