Grant Opportunities


Letter of Intent

The first step in the process of a grant application to The LAM Foundation is to submit a Letter of Intent (LOI). The submission of an LOI is required for each grant category. An applicant must submit an LOI in order to submit a grant application.

Application Timeline for In-Cycle Grants

With the exception of Travel Grants, The LAM Foundation requires all applicants to submit their LOI using the online application form available at our grant website (proposalCENTRAL).

Note: Applicants must create a profile and be logged in to proposalCENTRAL in order to access The LAM Foundation’s LOI Form. To aid applicants in navigating our online grant system, we offer a step-by-step tutorial by clicking here.

Inquiries or technical issues regarding proposalCENTRAL and the online application process should be directed to their customer support:
Toll Free Phone: 800-875-2562 option #2

Collaboration with Tuberous Sclerosis Alliance in Research Funding

The LAM Foundation has historically collaborated with the Tuberous Sclerosis Alliance to fund projects that fulfill the research mission of both organizations. You will be asked if you have or will be submitting your project to the Tuberous Sclerosis Alliance for funding in this grant cycle.

Grant Application

If your LOI is approved, The LAM Foundation will invite you to submit a full grant application. Click the following link for information and instructions regarding the submission of a grant application.

For information about The LAM Foundation’s in-cycle grant application process or requirements, please contact Judy Sheridan, Grant and Research Manager at


In-Cycle Research Grant Categories:


Pilot and Feasibility Grantplus

Funding Level: Maximum of $50,000 may be requested.
Period: Up to 1 year of support is available.

The objective of this grant is to provide funds to encourage the development and testing of new hypotheses and/or new methods in research areas relevant to LAM. Proposed work must be hypothesis generating or hypothesis testing, reflecting innovative approaches to important questions in LAM research or development of novel methods, and providing sufficient preliminary data to justify the Foundation’s support. Results from Pilot and Feasibility Grants should lead to the submission of applications for funding from other agencies (i.e. NIH). At the conclusion of the funding term, applicants are expected to apply for further funding by other mechanisms or from outside agencies. The award is not intended to support continuation of programs begun under other granting mechanisms.

FRANCIS X. McCORMACK, MD, Career Development Awardplus

In 2021, The LAM Foundation (TLF) Board of Directors renamed the Career Development Award to honor Dr. Francis X. McCormack's legacy. Dr. McCormack was the founding scientific director of TLF and tirelessly served the LAM community in this role for 25 years. Dr. McCormack was the leading architect behind the multiple transformative advancements in LAM, including, but not limited to, the development of a blood-based biomarker for disease diagnosis, FDA-approved treatment, and clinical practice guidelines. A key feature of Dr. McCormack's professional life included the selfless promotion of young investigators to empower them in their career pursuits. Dr. McCormack's dedication to the LAM community and the principle of keeping the LAM patients at the front and center of every decision has served as an inspiration for numerous investigators beginning their careers. The intent of this award is to develop future principal investigators who focus their time and energy advancing the field of LAM. It is our hope that the recipients of this award will help us carry Dr. McCormack's legacy forward by exhibiting a life-long dedication towards LAM research.

Funding Level: A maximum of $60,000 per year may be requested.
Period: Up to 3 years of support is available. Any funds remaining at the end of each year must be returned to the Foundation unless outlined in your originally submitted project budget or given prior approval. Payments for years two and three are contingent upon the availability of research funds, submission of respective progress reports, and report of expenditures satisfactory to the TLF grant's office.

This grant aims to provide support for both postdoctoral research fellows and investigators with less than five years in a faculty position who intend to pursue a career in LAM research. Applicants must indicate a commitment to LAM-related research by focusing 50% of their time on LAM in research or clinical practice. More than 50% of the funds must be used for the PI's salary support. The balance of the funds may be used for fringe benefits, supplies, or animal costs. No overhead or indirect costs are provided. To be eligible for the FXM CDA Grant, an applicant must:

  • Hold an M.D., Ph.D., or equivalent degrees;
  • Be qualified to conduct a program of original research under the supervision of an Independent Investigator;
  • Have an acceptable research plan for LAM;
  • Have access to institutional resources necessary to conduct the proposed research project;
  • Be no more than 120 months (10 years) from receiving their terminal research degree or end of post-graduate clinical training.
  • Not have been funded under a TLF Career Development Grant in the past.

An applicant may resubmit their original application with revisions up to two (2) times. However, an applicant who is resubmitting an application may be no more than 120 months (10 years) from receiving their terminal research degree or end of post-graduate clinical training.

Established Investigator Research Grantplus

Funding Level: Maximum of $50,000 per year may be requested.
Period: Up to 3 years. This award may be condensed to two years should the investigator request it. Any funds remaining at the end of each year must be returned to the Foundation unless outlined in your originally submitted project budget or given prior approval.

The objective of this grant is to provide funds to faculty level investigators for technician support and supplies to encourage the development of new information that contributes to the understanding of the basic biology of LAM expression, and the pathogenesis/management of LAM. In addition, consideration will be given to those projects that provide insight into the development of information that may contribute to new therapies for LAM. All proposals must be hypothesis generating or hypothesis testing and provide sufficient preliminary data to justify The LAM Foundation’s support.

Travel Grantplus

Funding Level: $1,000

The LAM Foundation sends out a “Call for Abstracts” prior to certain LAM International Research Conferences. Abstracts will be reviewed by the conference organizers and members of the Scientific Advisory Board. Platform Presentations will be selected from submitted abstracts based on scientific merit and thematic considerations. A travel grant will be awarded to those selected as Platform Presenters. Notification of acceptance and selection for presentation will be issued to the submitting author via email. This will provide time for presenters to register for the conference and allow travel grant awardees to make airline reservations at least 3 weeks in advance.




The LAM Foundation also considers proposals for clinical trials, bridge funding and other special projects.

Please contact The LAM Foundation at for information about the Foundation's out-of-cycle grant opportunities.